MyBioSource.com's MOUSE ANTI HUMAN CD41 is a Mouse monoclonal antibody. The MOUSE ANTI HUMAN CD41 Antibody was generated using CD41, CD41b, GpIIb, HPA3, integrin, alpha 2b, and ITGA2B as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Mouse anti Human CD41 antibody, clone PM6/248 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex